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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 936444Generated: October 25, 2026

Tetrahydrofuran → tert-butyl 5-amino-2-[7-[[4-(chloromethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoate

https://huagongshe.com/reaction/936444

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantDiisopropyl diazene-1,2-dicarboxylateHCID 75555—
Reactant[4-(Chloromethyl)phenyl]methanolHCID 5107660—
Reactanttert-butyl 5-amino-2-(7-hydroxy-3-oxo-1H-isoindol-2-yl)-5-oxopentanoateHCID 67334268—
Producttert-butyl 5-amino-2-[7-[[4-(chloromethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoateHCID 67335016—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-556ab625210443f383323f72ab82f68c
Source noteValidation data from https://doi.org/10.1039/C8SC04228D