Butanal → 1-(5-Bromopyridin-2-yl)butan-1-ol

HRID 936449Notes

Reaction equation

HRID 936449 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([Br:8])[cH:6][cH:7]1.[CH2:9]([Li:10])[CH2:11][CH2:12][CH3:13].[CH3:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1.[CH:14]([CH2:15][CH2:16][CH3:17])=[O:18]>>[c:2]1([CH:14]([CH2:15][CH2:16][CH3:17])[OH:18])[n:3][cH:4][c:5]([Br:8])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 261ButanalHCID 1140TolueneHCID 693532,5-DibromopyridineHCID 178418339Butyllithium

Product 1

HCID 121577811-(5-Bromopyridin-2-yl)butan-1-ol

Sources & evidence

ORD record
ord-c5a3abefec104034959e327505b56dbe
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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