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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 936453Generated: October 25, 2026

Tetrahydrofuran → 2-Butyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester

https://huagongshe.com/reaction/936453

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantButyl iodideHCID 10962—
ReactantLithium ionHCID 28486—
Reactant1-Tert-butyl 2-methyl pyrrolidine-1,2-dicarboxylateHCID 394147—
ReactantNpc316347HCID 3280088—
Product2-Butyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl esterHCID 66687218—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-fb7f097ba27e419ea63fc1765ea871b7
Source noteValidation data from https://doi.org/10.1039/C8SC04228D