Dichloromethane → 6-(6,7-dimethoxyquinolin-4-yl)oxy-N-(2-fluorocyclopropyl)naphthalene-1-carboxamide
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]4[cH:19][cH:20][cH:21][c:22]([C:26](=[O:27])[Cl:28])[c:23]4[cH:24][cH:25]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[Cl:34][CH2:35][Cl:36].[F:29][CH:30]1[CH:31]([NH2:33])[CH2:32]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]4[cH:19][cH:20][cH:21][c:22]([C:26](=[O:27])[NH:33][CH:31]5[CH:30]([F:29])[CH2:32]5)[c:23]4[cH:24][cH:25]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]Participants
4
Sources & evidence
- ORD record
- ord-87292787e56b408691ae2f1755a99c44
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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