1-[(Pyrrolidin-2-yl)methyl]piperidine → [2-(Piperidin-1-ylmethyl)pyrrolidin-1-yl]-[5-(trifluoromethyl)-1-benzofuran-2-yl]methanone
Reaction equation
[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:8][c:9]([C:11](=[O:12])[OH:13])[o:10]2)[cH:14]1)([F:15])[F:16].[NH:17]1[CH:18]([CH2:22][N:23]2[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]2)[CH2:19][CH2:20][CH2:21]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:8][c:9]([C:11](=[O:13])[N:17]3[CH:18]([CH2:22][N:23]4[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]4)[CH2:19][CH2:20][CH2:21]3)[o:10]2)[cH:14]1)([F:15])[F:16]Participants
3
Sources & evidence
- ORD record
- ord-c85801a163cd416f92ded936a7753284
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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