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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 936664Generated: October 26, 2026

Tetrahydrofuran → methyl 5-amino-4-[7-[[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-3-yl]methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoate

https://huagongshe.com/reaction/936664

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantDiisopropyl diazene-1,2-dicarboxylateHCID 75555—
ReactantMethyl 5-amino-4-(4-hydroxy-1-oxoisoindolin-2-yl)-5-oxopentanoateHCID 58389139—
Reactant[1-Methyl-5-(morpholin-4-ylmethyl)pyrazol-3-yl]methanolHCID 67334047—
Productmethyl 5-amino-4-[7-[[1-methyl-5-(morpholin-4-ylmethyl)pyrazol-3-yl]methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoateHCID 67336623—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3dd7263c2d414bf69ead4ae42ed1a6b5
Source noteValidation data from https://doi.org/10.1039/C8SC04228D