Ethanol → Ethyl 4-[(5-phenylpentyl)amino]benzoate

HRID 936688Notes

Reaction equation

HRID 936688 reaction equation
[CH3:27][N:28]([P:29]([N:30]([CH3:31])[CH3:32])([N:33]([CH3:34])[CH3:35])=[O:36])[CH3:37].[CH3:38][CH2:39][OH:40].[I-:14].[NH2:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12]1.[Na+:13].[OH2:41].[c:15]1([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][Cl:26])[cH:16][cH:17][cH:18][cH:19][cH:20]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12]1)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1

Participants

8

Reactant 7

HCID 702EthanolHCID 923Sodium ionHCID 962WaterHCID 2337BenzocaineHCID 12679HexamethylphosphoramideHCID 30165Iodide IonHCID 5191731-Chloro-5-phenylpentane

Product 1

HCID 13079663Ethyl 4-[(5-phenylpentyl)amino]benzoate

Sources & evidence

ORD record
ord-6122ed50aa344f99be0d60da896410d7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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