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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 936719Generated: October 29, 2026

Dimethylformamide → 5-[(1H-Indazol-4-ylmethyl)-carbamoyl]-3-isopropyl-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/936719

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantO-benzotriazol-1-yl-tetramethyluroniumHCID 130500—
Reactant1-(1H-Indazol-4-yl)methanamineHCID 44119277—
Reactant4-Isopropyl-5-(methoxycarbonyl)thiophene-2-carboxylic acidHCID 68227096—
Product5-[(1H-Indazol-4-ylmethyl)-carbamoyl]-3-isopropyl-thiophene-2-carboxylic acid methyl esterHCID 68226795—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3471f8a1398149af8f4672c65a6fe539
Source noteValidation data from https://doi.org/10.1039/C8SC04228D