Pyridine → N-{1-[1-(4-Chloro-benzoyl)-4-hydroxy-pyrrolidin-3-yl]-piperidin-4-yl}-N-(4-chloro-phenyl)-acetamide

HRID 93672Notes

Reaction equation

HRID 93672 reaction equation
[CH3:30][C:31](=[O:32])[O:33][C:34]([CH3:35])=[O:36].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH:12]([N:16]3[CH2:17][CH2:18][CH:19]([NH:22][c:23]4[cH:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]4)[CH2:20][CH2:21]3)[CH:13]([OH:15])[CH2:14]2)[cH:6][cH:7]1.[cH:37]1[cH:38][cH:39][n:40][cH:41][cH:42]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH:12]([N:16]3[CH2:17][CH2:18][CH:19]([N:22]([c:23]4[cH:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]4)[C:31]([CH3:30])=[O:32])[CH2:20][CH2:21]3)[CH:13]([OH:15])[CH2:14]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 7918Acetic AnhydrideHCID 68512735HCID 68512735, compound

Product 1

HCID 68511424N-{1-[1-(4-Chloro-benzoyl)-4-hydroxy-pyrrolidin-3-yl]-piperidin-4-yl}-N-(4-chloro-phenyl)-acetamide

Sources & evidence

ORD record
ord-34f74de6e9994c4cb4b11814cf28ecfc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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