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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 93675Generated: October 25, 2026

Hydrochloric Acid → 6-(4-Chlorophenyl)-5-(5-chloro-3-pyridinyl)-1-(1-hydroxybutan-2-yl)-3-methyl-3-prop-2-enylpiperidin-2-one

https://huagongshe.com/reaction/93675

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTrimethylamineHCID 1146—
ReactantAcetonitrileHCID 6342—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantToluene-p-sulphonic anhydrideHCID 77773—
Reactant2-[3-(4-chlorophenyl)-2-(5-chloro-3-pyridinyl)-3-hydroxypropyl]-N-(1-hydroxybutan-2-yl)-2-methylpent-4-enamideHCID 76834358—
Product6-(4-Chlorophenyl)-5-(5-chloro-3-pyridinyl)-1-(1-hydroxybutan-2-yl)-3-methyl-3-prop-2-enylpiperidin-2-oneHCID 76834675—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-a632222c49434496b171a08f871e1ad0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)