6-Chloro-1,2,3,4-tetrahydroisoquinoline → (6-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)-(2-diethylamino-5-methanesulfonyl-phenyl)-methanone
Reaction equation
[CH2:12]([CH3:13])[N:14]([c:15]1[c:16]([C:17](=[O:18])[OH:19])[cH:20][c:21]([S:24](=[O:25])(=[O:26])[CH3:27])[cH:22][cH:23]1)[CH2:28][CH3:29].[Cl:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][NH:7][CH2:6][CH2:5]2>>[Cl:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([C:17]([c:16]1[c:15]([N:14]([CH2:12][CH3:13])[CH2:28][CH3:29])[cH:23][cH:22][c:21]([S:24](=[O:25])(=[O:26])[CH3:27])[cH:20]1)=[O:18])[CH2:6][CH2:5]2Participants
3
Sources & evidence
- ORD record
- ord-68105b512d6b4e41bcebc5ca2c250a12
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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