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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 936828Generated: October 30, 2026

Bromide ion → 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one

https://huagongshe.com/reaction/936828

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromide ionHCID 259—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantChlorodifluoromethaneHCID 6372—
ReactantCyclohexaneHCID 8078—
ReactantTetrabutylammoniumHCID 16028—
ReactantHCID 135688047HCID 135688047—
Product2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-oneHCID 13961806—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-1fb848cfa44543b8ad6b679ebaf474e4
Source noteValidation data from https://doi.org/10.1039/C8SC04228D