5-fluoro-1,3-dihydro-2H-indol-2-one → 5-(2-dimethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-5,6,7,8-tetrahydro-1H-pyrrolo[3,2-c]azepin-4-one
Reaction equation
[CH3:1][N:2]([CH2:3][CH2:4][N:5]1[C:6](=[O:18])[c:7]2[c:8]([nH:12][c:13]([CH:16]=[O:17])[c:14]2[CH3:15])[CH2:9][CH2:10][CH2:11]1)[CH3:19].[F:20][c:21]1[cH:22][c:23]2[c:27]([cH:28][cH:29]1)[NH:26][C:25](=[O:30])[CH2:24]2>>[CH3:1][N:2]([CH2:3][CH2:4][N:5]1[C:6](=[O:18])[c:7]2[c:8]([nH:12][c:13]([CH:16]=[C:24]3[c:23]4[cH:22][c:21]([F:20])[cH:29][cH:28][c:27]4[NH:26][C:25]3=[O:30])[c:14]2[CH3:15])[CH2:9][CH2:10][CH2:11]1)[CH3:19]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-408b6e6520e5439cade4e192e0d7ee35
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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