Dimethylamine → N-[2-(N,N-Dimethylamino)pyrimidin-5-yl]-5-trifluoromethyl-1-(3-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Reaction equation
[CH3:32][NH:33][CH3:34].[CH3:35][CH2:36][OH:37].[Cl:1][c:2]1[n:3][cH:4][c:5]([NH:8][C:9](=[O:10])[c:11]2[cH:12][c:13]3[c:14]([n:15][cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[cH:18]3)[n:23]2[CH2:24][c:25]2[cH:26][c:27]([F:31])[cH:28][cH:29][cH:30]2)[cH:6][n:7]1>>[c:2]1([N:33]([CH3:32])[CH3:34])[n:3][cH:4][c:5]([NH:8][C:9](=[O:10])[c:11]2[cH:12][c:13]3[c:14]([n:15][cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[cH:18]3)[n:23]2[CH2:24][c:25]2[cH:26][c:27]([F:31])[cH:28][cH:29][cH:30]2)[cH:6][n:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-8c3631c16e9341fdb14e6ac24452f21b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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