2-Chlorophenylboronic acid → 5-(2-Chlorophenyl)-4-(4-chlorophenyl)-2-fluoropyridine

HRID 936980Notes

Reaction equation

HRID 936980 reaction equation
[Cl:16][c:17]1[c:18]([B:23]([OH:24])[OH:25])[cH:19][cH:20][cH:21][cH:22]1.[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][cH:11][c:12]([Cl:15])[cH:13][cH:14]2)[cH:4][c:5]([F:8])[n:6][cH:7]1.[Cl:26][c:27]1[cH:28][cH:29][cH:30][cH:31][c:32]1-[c:33]1[c:34](-[c:35]2[cH:36][cH:37][c:38]([Cl:39])[cH:40][cH:41]2)[cH:42][c:43]2[n:44]([c:45](=[O:46])[n:47]([CH2:48][c:49]3[cH:50][n:51][c:52]([C:53]([F:54])([F:55])[F:56])[cH:57][cH:58]3)[n:59]2)[c:60]1[CH3:61]>>[c:2]1(-[c:18]2[c:17]([Cl:16])[cH:22][cH:21][cH:20][cH:19]2)[c:3](-[c:9]2[cH:10][cH:11][c:12]([Cl:15])[cH:13][cH:14]2)[cH:4][c:5]([F:8])[n:6][cH:7]1

Participants

4

Reactant 3

HCID 27343222-Chlorophenylboronic acidHCID 577993616-(2-chlorophenyl)-7-(4-chlorophenyl)-5-methyl-2-((6-(trifluoromethyl)pyridin-3-yl)methyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneHCID 577994555-Chloro-4-(4-chlorophenyl)-2-fluoropyridine

Product 1

HCID 577994125-(2-Chlorophenyl)-4-(4-chlorophenyl)-2-fluoropyridine

Sources & evidence

ORD record
ord-af6a33566ba14d90aa46a39ad9295678
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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