Ethyl 5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-carboxylate → (3-(3-Chloro-4-((dimethylamino)methyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone

HRID 937046Notes

Reaction equation

HRID 937046 reaction equation
[CH3:17][O:18][c:19]1[cH:20][cH:21][c:22](-[c:25]2[n:26][n:27][c:28]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[o:29]2)[cH:23][cH:24]1.[NH:1]1[CH2:2][CH:3]([O:5][c:6]2[cH:7][c:8]([Cl:16])[c:9]([CH2:12][N:13]([CH3:14])[CH3:15])[cH:10][cH:11]2)[CH2:4]1>>[N:1]1([C:30]([c:28]2[n:27][n:26][c:25](-[c:22]3[cH:21][cH:20][c:19]([O:18][CH3:17])[cH:24][cH:23]3)[o:29]2)=[O:31])[CH2:2][CH:3]([O:5][c:6]2[cH:7][c:8]([Cl:16])[c:9]([CH2:12][N:13]([CH3:14])[CH3:15])[cH:10][cH:11]2)[CH2:4]1

Participants

3

Reactant 2

HCID 13407471Ethyl 5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-carboxylateHCID 666534891-(4-(Azetidin-3-yloxy)-2-chlorophenyl)-N,N-dimethylmethanamine

Product 1

HCID 56598400(3-(3-Chloro-4-((dimethylamino)methyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone

Sources & evidence

ORD record
ord-c5551ad94e3845b48d1ef01cabf5d6d5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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