Methanol → 8-Chloro-1-ethyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Reaction equation
[CH3:23][OH:24].[F:1][C:2]([F:3])([F:4])[C:19]([N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:14][c:15]([Cl:18])[cH:16][cH:17]2)[CH:10]([CH2:12][CH3:13])[CH2:11]1)=[O:20].[Na+:22].[OH-:21]>>[NH:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:14][c:15]([Cl:18])[cH:16][cH:17]2)[CH:10]([CH2:12][CH3:13])[CH2:11]1Participants
5
Sources & evidence
- ORD record
- ord-5a8bcab3ed7148098a8b2e646595e7d7
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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