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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 937245Generated: October 31, 2026

6-fluoro-1H-benzimidazole-2-thiol → 2-[4-[2-(5-fluorobenzimidazol-2-ylthio)ethyl]piperazin-1-yl]-N-[2,4-bis(2,2,2-trifluoroethoxy)-6-methylpyridin-3-yl]acetamide

https://huagongshe.com/reaction/937245

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-fluoro-1H-benzimidazole-2-thiolHCID 3434885—
Reactant2-[4-(2-hydroxyethyl)piperazin-1-yl]-N-[2,4-bis(methylthio)-6-methyl-3-pyridyl]acetamideHCID 11689240—
Reactant2-[4-(2-hydroxyethyl)piperazin-1-yl]-N-[2,4 bis(2,2,2-trifluoroethoxy)-6-methylpyridin-3-yl]acetamideHCID 23110955—
ReactantHCID 178527775HCID 178527775—
Product2-[4-[2-(5-fluorobenzimidazol-2-ylthio)ethyl]piperazin-1-yl]-N-[2,4-bis(2,2,2-trifluoroethoxy)-6-methylpyridin-3-yl]acetamideHCID 23116159—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-16ee04bb3c464b2a8fe2db4acd09ab36
Source noteValidation data from https://doi.org/10.1039/C8SC04228D