1-Benzyloxy-2-iodoethane → tert-butyl (1RS,2RS,3RS,5SR)-3-[4-(2-benzyloxy-ethoxymethyl)-phenyl]-2-(naphthalen-2-ylmethoxy)-8-aza-bicyclo[3.2.1]octane-8-carboxylate
Reaction equation
[CH2:36]([c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1)[O:43][CH2:44][CH2:45][I:46].[OH:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[CH:10]([O:24][CH2:25][c:26]3[cH:27][c:28]4[cH:29][cH:30][cH:31][cH:32][c:33]4[cH:34][cH:35]3)[CH:11]3[CH2:12][CH2:13][CH:14]([CH2:15]2)[N:16]3[C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[cH:7][cH:8]1>>[O:1]([CH2:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[CH:10]([O:24][CH2:25][c:26]3[cH:27][c:28]4[cH:29][cH:30][cH:31][cH:32][c:33]4[cH:34][cH:35]3)[CH:11]3[CH2:12][CH2:13][CH:14]([CH2:15]2)[N:16]3[C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[cH:7][cH:8]1)[CH2:45][CH2:44][O:43][CH2:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ae8003191da442b581b2fa13dc2cb388
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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