Methanol → (3-amino-2,6-difluoro-phenyl)-(5-pyridin-3-yl-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone

HRID 937402Notes

Reaction equation

[CH2:1]([N:8]([CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:44]1)[c:9]1[c:10]([F:43])[c:11]([C:16](=[O:17])[c:18]2[cH:19][n:20]([Si:33]([CH:34]([CH3:35])[CH3:36])([CH:37]([CH3:38])[CH3:39])[CH:40]([CH3:41])[CH3:42])[c:21]3[n:22][cH:23][c:24](-[c:27]4[cH:28][n:29][cH:30][cH:31][cH:32]4)[cH:25][c:26]23)[c:12]([F:15])[cH:13][cH:14]1)[c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1.[CH3:53][OH:54].[H:51][H:52].[OH-:55].[OH-:57].[Pd+2:56]>>[NH2:8][c:9]1[c:10]([F:43])[c:11]([C:16](=[O:17])[c:18]2[cH:19][n:20]([Si:33]([CH:34]([CH3:35])[CH3:36])([CH:37]([CH3:38])[CH3:39])[CH:40]([CH3:41])[CH3:42])[c:21]3[n:22][cH:23][c:24](-[c:27]4[cH:28][n:29][cH:30][cH:31][cH:32]4)[cH:25][c:26]23)[c:12]([F:15])[cH:13][cH:14]1