Dichloromethane → 3-[2-(trifluoromethyl)-4'-methoxybenzhydryloxy]-N-(tert-butyl)-azetidine-1-carboxamide
Reaction equation
[C:25]([CH3:26])([CH3:27])([CH3:28])[N:29]=[C:30]=[O:31].[Cl:32][CH2:33][Cl:34].[F:1][C:2]([c:3]1[c:4]([CH:5]([c:6]2[cH:7][cH:8][c:9]([O:12][CH3:13])[cH:10][cH:11]2)[O:14][CH:15]2[CH2:16][NH:17][CH2:18]2)[cH:19][cH:20][cH:21][cH:22]1)([F:23])[F:24]>>[F:1][C:2]([c:3]1[c:4]([CH:5]([c:6]2[cH:7][cH:8][c:9]([O:12][CH3:13])[cH:10][cH:11]2)[O:14][CH:15]2[CH2:16][N:17]([C:30]([NH:29][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:31])[CH2:18]2)[cH:19][cH:20][cH:21][cH:22]1)([F:23])[F:24]Participants
4
Sources & evidence
- ORD record
- ord-292368a5009d4114a7b2198a92a13bc5
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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