Ethanol → 1-Bromo-3-fluoro-5-nitrobenzene

HRID 937467Notes

Reaction equation

HRID 937467 reaction equation
[Br:1][c:2]1[c:3]([NH2:12])[c:4]([N+:9](=[O:10])[O-:11])[cH:5][c:6]([F:8])[cH:7]1.[CH3:17][CH2:18][OH:19].[N:13]([O-:14])=[O:15].[Na+:16].[OH2:20].[OH2:21].[OH2:22].[OH2:23].[OH2:24].[OH2:25].[OH2:26].[OH2:37].[S:27]([OH:28])([OH:29])(=[O:30])=[O:31].[S:32](=[O:33])(=[O:34])([OH:35])[OH:36]>>[Br:1][c:2]1[cH:3][c:4]([N+:9](=[O:10])[O-:11])[cH:5][c:6]([F:8])[cH:7]1

Participants

7

Reactant 6

HCID 702EthanolHCID 923Sodium ionHCID 946NitriteHCID 962Water8×HCID 1118Sulfuric Acid2×HCID 2920042-Bromo-4-fluoro-6-nitroaniline

Product 1

HCID 150201571-Bromo-3-fluoro-5-nitrobenzene

Sources & evidence

ORD record
ord-7e4d0ed038a04bcaa7688057eeebdf81
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…