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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 937580Generated: October 30, 2026

Citric Acid → 1'-[4-(2-hydroxyethoxy)benzyl]-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

https://huagongshe.com/reaction/937580

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCitric AcidHCID 311—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantBorohydrideHCID 28123—
ReactantLithium ionHCID 28486—
Reactantethyl {4-[(2'-oxo-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-1'(2'H)-yl)methyl]phenoxy}acetateHCID 45280338—
Product1'-[4-(2-hydroxyethoxy)benzyl]-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-oneHCID 45280340—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-7ee50b21c7b945a09ad250ec1203e1ad
Source noteValidation data from https://doi.org/10.1039/C8SC04228D