6-(4-Ethylpiperazin-1-yl)pyridin-3-amine → N-(3-(2-(6-(4-Ethylpiperazin-1-yl)pyridin-3-ylamino)thieno[3,2-d]pyrimidin-7-yl)phenyl)-N-methylmethanesulfonamide

HRID 937671Notes

Reaction equation

HRID 937671 reaction equation
[CH2:23]([CH3:24])[N:25]1[CH2:26][CH2:27][N:28]([c:31]2[cH:32][cH:33][c:34]([NH2:37])[cH:35][n:36]2)[CH2:29][CH2:30]1.[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:7]1)[c:8](-[c:11]1[cH:12][c:13]([N:17]([S:18](=[O:19])(=[O:20])[CH3:21])[CH3:22])[cH:14][cH:15][cH:16]1)[cH:9][s:10]2>>[c:2]1([NH:37][c:34]2[cH:33][cH:32][c:31]([N:28]3[CH2:27][CH2:26][N:25]([CH2:23][CH3:24])[CH2:30][CH2:29]3)[n:36][cH:35]2)[n:3][cH:4][c:5]2[c:6]([n:7]1)[c:8](-[c:11]1[cH:12][c:13]([N:17]([S:18](=[O:19])(=[O:20])[CH3:21])[CH3:22])[cH:14][cH:15][cH:16]1)[cH:9][s:10]2

Participants

3

Reactant 2

HCID 91616746-(4-Ethylpiperazin-1-yl)pyridin-3-amineHCID 86673223N-(3-(2-chlorothieno[3,2-d]pyrimidin-7-yl)phenyl)-N-methylmethanesulfonamide

Product 1

HCID 52932074N-(3-(2-(6-(4-Ethylpiperazin-1-yl)pyridin-3-ylamino)thieno[3,2-d]pyrimidin-7-yl)phenyl)-N-methylmethanesulfonamide

Sources & evidence

ORD record
ord-b43dbd0cf4c94b7cafd9e6c284499abb
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…