2-Methylbenzoic acid → N-Ethyl-2-methyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]benzamide

HRID 937699Notes

Reaction equation

HRID 937699 reaction equation
[CH2:11]([CH3:12])[NH:13][CH2:14][C:15]([C:16]([F:17])([F:18])[F:19])([OH:20])[CH2:21][NH:22][c:23]1[c:24]2[cH:25][n:26][n:27](-[c:32]3[cH:33][cH:34][c:35]([F:38])[cH:36][cH:37]3)[c:28]2[cH:29][cH:30][cH:31]1.[CH3:1][c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[C:8]([OH:9])=[O:10]>>[CH3:1][c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[C:8](=[O:10])[N:13]([CH2:11][CH3:12])[CH2:14][C:15]([C:16]([F:17])([F:18])[F:19])([OH:20])[CH2:21][NH:22][c:23]1[c:24]2[cH:25][n:26][n:27](-[c:32]3[cH:33][cH:34][c:35]([F:38])[cH:36][cH:37]3)[c:28]2[cH:29][cH:30][cH:31]1

Participants

3

Reactant 2

HCID 83732-Methylbenzoic acidHCID 593241253-(Ethylamino)-1,1,1-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-propanol

Product 1

HCID 24937934N-Ethyl-2-methyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]benzamide

Sources & evidence

ORD record
ord-e231ceeb06d0448ba0bfc57ebcf4e6d8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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