Carbonate Ion → 6-Chloro-4-(5-(methoxymethyl)-1-methyl-1H-pyrazol-3-ylamino)-2-methylpyridazin-3(2H)-one

HRID 937748Notes

Reaction equation

HRID 937748 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][n:13]([CH3:19])[c:14]([CH2:16][O:17][CH3:18])[cH:15]2)[c:5](=[O:6])[n:7]([CH3:8])[cH:9]1.[Br:20][c:21]1[c:22](=[O:29])[n:23]([CH3:28])[n:24][c:25]([Cl:27])[cH:26]1.[C:30](=[O:31])([O-:32])[O-:33].[CH2:36]1[O:37][CH2:38][CH2:39][O:40][CH2:41]1.[Cs+:34].[Cs+:35]>>[NH:10]([c:11]1[n:12][n:13]([CH3:19])[c:14]([CH2:16][O:17][CH3:18])[cH:15]1)[c:21]1[c:22](=[O:29])[n:23]([CH3:28])[n:24][c:25]([Cl:27])[cH:26]1

Participants

6

Reactant 5

HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 580441025-Bromo-3-(5-(methoxymethyl)-1-methyl-1H-pyrazol-3-ylamino)-1-methylpyridin-2(1H)-oneHCID 592164744-Bromo-6-chloro-2-methyl-2,3-dihydropyridazin-3-one

Product 1

HCID 580438316-Chloro-4-(5-(methoxymethyl)-1-methyl-1H-pyrazol-3-ylamino)-2-methylpyridazin-3(2H)-one

Sources & evidence

ORD record
ord-244df70e20c8438cbeb31bb566bc94b8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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