5-Chloro-2-propyl-[1,8]naphthyridine → 4-[4-Chloro-2-(7-propyl-[1,8]naphthyridin-4-ylamino)-phenoxy]-N-(2-methoxy-ethyl)-benzamide
Reaction equation
[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6]([CH2:12][CH2:13][CH3:14])[n:7][c:8]2[n:9][cH:10][cH:11]1.[NH2:15][c:16]1[c:17]([O:18][c:19]2[cH:20][cH:21][c:22]([C:23](=[O:24])[NH:25][CH2:26][CH2:27][O:28][CH3:29])[cH:30][cH:31]2)[cH:32][cH:33][c:34]([Cl:36])[cH:35]1>>[c:2]1([NH:15][c:16]2[c:17]([O:18][c:19]3[cH:20][cH:21][c:22]([C:23](=[O:24])[NH:25][CH2:26][CH2:27][O:28][CH3:29])[cH:30][cH:31]3)[cH:32][cH:33][c:34]([Cl:36])[cH:35]2)[c:3]2[cH:4][cH:5][c:6]([CH2:12][CH2:13][CH3:14])[n:7][c:8]2[n:9][cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-1a4595de9341487cab06b5a2c973a242
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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