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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 93783Generated: October 25, 2026

Dichloromethane → 6-[1-(Pyridin-4-yl)piperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/93783

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantDiisopropyl diazene-1,2-dicarboxylateHCID 75555—
Reactanttert-Butyl 6-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylateHCID 10060623—
Reactant(1-(Pyridin-4-YL)piperidin-4-YL)methanolHCID 11310048—
Product6-[1-(Pyridin-4-yl)piperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl esterHCID 60064178—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-550e118ffdb14e9f983513409c493a99
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)