Pyridine → 1-(3-Benzyloxy-propyl)-cyclopropanesulfonic acid [7-(2-fluoro-4-iodo-phenylamino)-6-methyl-5-oxo-2,3-dihydro-5H-oxazolo[3,2-a]pyridin-8-yl]-amide
Reaction equation
[CH2:22]([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[O:29][CH2:30][CH2:31][CH2:32][C:33]1([S:36](=[O:37])(=[O:38])[Cl:39])[CH2:34][CH2:35]1.[NH2:1][c:2]1[c:3]2[n:4]([c:5](=[O:18])[c:6]([CH3:17])[c:7]1[NH:8][c:9]1[c:10]([F:16])[cH:11][c:12]([I:15])[cH:13][cH:14]1)[CH2:19][CH2:20][O:21]2.[cH:40]1[cH:41][cH:42][n:43][cH:44][cH:45]1>>[NH:1]([c:2]1[c:3]2[n:4]([c:5](=[O:18])[c:6]([CH3:17])[c:7]1[NH:8][c:9]1[c:10]([F:16])[cH:11][c:12]([I:15])[cH:13][cH:14]1)[CH2:19][CH2:20][O:21]2)[S:36]([C:33]1([CH2:32][CH2:31][CH2:30][O:29][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:34][CH2:35]1)(=[O:37])=[O:38]Participants
4
Sources & evidence
- ORD record
- ord-c1f259f0ccd1428fb06ac4992697cde5
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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