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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 937935Generated: November 1, 2026

Hydrochloric Acid → N-(3,5-Difluoro-benzyl)-2-methyl-malonamic acid ethyl ester

https://huagongshe.com/reaction/937935

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTetrahydrofuranHCID 8028—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
ReactantDiisopropylethylamineHCID 81531—
Reactant3,5-DifluorobenzylamineHCID 145211—
Reactant2-Methyl-malonic acid monoethyl esterHCID 295972—
ProductN-(3,5-Difluoro-benzyl)-2-methyl-malonamic acid ethyl esterHCID 69280082—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-a4b4e1e8cee440639dd8ef8cf6236501
Source noteValidation data from https://doi.org/10.1039/C8SC04228D