2-(5-Bromo-2-chloropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid → 2-(5-Bromo-2-chloropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid [bis-(4-methoxyphenyl)-methyl]-amide
Reaction equation
[Br:38][c:39]1[c:40](-[c:41]2[s:42][c:43]3[cH:44][cH:45][cH:46][c:47]([C:48]([OH:49])=[O:50])[c:51]3[cH:52]2)[n:53][c:54]([Cl:55])[n:56][cH:57]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:9]([c:10]2[cH:11][cH:12][c:13]([O:16][CH3:17])[cH:14][cH:15]2)[NH:18][C:19](=[O:20])[c:21]2[cH:22][cH:23][cH:24][c:25]3[s:26][c:27](-[c:30]4[n:31][c:32]([Cl:37])[n:33][cH:34][c:35]4[CH3:36])[cH:28][c:29]23)[cH:7][cH:8]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:9]([c:10]2[cH:11][cH:12][c:13]([O:16][CH3:17])[cH:14][cH:15]2)[NH:18][C:19](=[O:20])[c:21]2[cH:22][cH:23][cH:24][c:25]3[s:26][c:27](-[c:30]4[n:31][c:32]([Cl:37])[n:33][cH:34][c:35]4[Br:38])[cH:28][c:29]23)[cH:7][cH:8]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-cff05a0b483841dc8fe8a213e17a725b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…