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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 938031Generated: November 1, 2026

Hydrochloric Acid → 2-[4-(4-{[2-Amino-6-(trifluoromethyl)pyrimidin-4-yl]amino}-2-fluorophenoxy)-1H-pyrrolo[2,3-b]pyridin-3-yl]ethanol

https://huagongshe.com/reaction/938031

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
Reactant4-Chloro-6-(trifluoromethyl)pyrimidin-2-amineHCID 13086907—
Reactant2-[4-(4-Amino-2-fluorophenoxy)-1H-pyrrolo[2,3-b]pyridin-3-yl]ethanolHCID 21081544—
Product2-[4-(4-{[2-Amino-6-(trifluoromethyl)pyrimidin-4-yl]amino}-2-fluorophenoxy)-1H-pyrrolo[2,3-b]pyridin-3-yl]ethanolHCID 11568564—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-8037af62ffee4907a658ebead9cb7e69
Source noteValidation data from https://doi.org/10.1039/C8SC04228D