Water → Methyl 4-acetamidosalicylate

HRID 938059Notes

Reaction equation

HRID 938059 reaction equation
[CH3:19][C:20]([Cl:21])=[O:22].[Cl:23][CH2:24][Cl:25].[NH2:1][c:2]1[cH:3][c:4]([OH:12])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[OH2:26].[cH:13]1[cH:14][cH:15][n:16][cH:17][cH:18]1>>[NH:1]([c:2]1[cH:3][c:4]([OH:12])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1)[C:20]([CH3:19])=[O:22]

Participants

6

Reactant 5

HCID 962WaterHCID 1049PyridineHCID 6344DichloromethaneHCID 6367Acetyl chlorideHCID 77787Methyl p-aminosalicylate

Product 1

HCID 77719Methyl 4-acetamidosalicylate

Sources & evidence

ORD record
ord-5fe32357f7ff4a39981b7b06682f41eb
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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