3-Fluoro-4-(2-(4-(methylsulfonyl)phenyl)thieno[3,2-b]pyridin-7-yloxy)benzenamine → N-(3-Fluoro-4-(2-(4-hydroxyphenyl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Reaction equation
[F:1][c:2]1[cH:3][c:4]([NH:28][C:29](=[S:30])[NH:31][C:32]([CH2:33][c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)=[O:40])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[cH:19][cH:20][c:21]([S:24]([CH3:25])(=[O:26])=[O:27])[cH:22][cH:23]1)[s:17]2.[F:41][c:42]1[cH:43][c:44]([NH2:45])[cH:46][cH:47][c:49]1[O:48][c:50]1[cH:51][cH:52][n:53][c:54]2[cH:55][c:56](-[c:57]3[cH:58][cH:59][c:60]([S:61]([CH3:62])(=[O:63])=[O:64])[cH:65][cH:66]3)[s:67][c:68]12.[NH2:69][c:70]1[cH:71][cH:72][c:73]([O:74][c:75]2[cH:76][cH:77][n:78][c:79]3[cH:80][c:81](-[c:82]4[cH:83][cH:84][c:85]([OH:86])[cH:87][cH:88]4)[s:89][c:90]23)[c:91]([F:92])[cH:93]1>>[F:1][c:2]1[cH:3][c:4]([NH:28][C:29](=[S:30])[NH:31][C:32]([CH2:33][c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)=[O:40])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[cH:19][cH:20][c:21]([OH:48])[cH:22][cH:23]1)[s:17]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-f49cd3c42a2643a5bb609c31d70ba2ae
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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