Dichloromethane → 6-[({1-[2-(6-Hydroxy-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)ethyl]piperidin-4-yl)amino)methyl]-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

HRID 938283Notes

Reaction equation

HRID 938283 reaction equation
[B:35]([Br:36])([Br:37])[Br:38].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:34]1)[N:8]([CH2:13][CH2:14][N:15]1[CH2:16][CH2:17][CH:18]([NH:21][CH2:22][c:23]3[cH:24][cH:25][c:26]4[c:31]([n:32]3)[NH:30][C:29](=[O:33])[CH2:28][O:27]4)[CH2:19][CH2:20]1)[C:9](=[O:12])[CH2:10][O:11]2.[Cl:39][CH2:40][Cl:41]>>[OH:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:34]1)[N:8]([CH2:13][CH2:14][N:15]1[CH2:16][CH2:17][CH:18]([NH:21][CH2:22][c:23]3[cH:24][cH:25][c:26]4[c:31]([n:32]3)[NH:30][C:29](=[O:33])[CH2:28][O:27]4)[CH2:19][CH2:20]1)[C:9](=[O:12])[CH2:10][O:11]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 15983550HCID 15983550, compound

Product 1

HCID 159838106-[({1-[2-(6-Hydroxy-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)ethyl]piperidin-4-yl)amino)methyl]-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

Sources & evidence

ORD record
ord-8fe2d3d890a84059b168ffaf4e9caacd
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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