Water → N6-(trans-4-aminocyclohexyl)-N8-(4-aminophenyl)imidazo[1,2-b]pyridazine-6,8-diamine
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([NH:11][c:12]2[cH:13][cH:14][c:15]([NH2:18])[cH:16][cH:17]2)[c:5]2[n:6]([n:7]1)[cH:8][cH:9][n:10]2.[NH2:19][CH:20]1[CH2:21][CH2:22][CH:23]([NH2:26])[CH2:24][CH2:25]1.[OH2:27]>>[c:2]1([NH:26][CH:23]2[CH2:22][CH2:21][CH:20]([NH2:19])[CH2:25][CH2:24]2)[cH:3][c:4]([NH:11][c:12]2[cH:13][cH:14][c:15]([NH2:18])[cH:16][cH:17]2)[c:5]2[n:6]([n:7]1)[cH:8][cH:9][n:10]2Participants
4
Sources & evidence
- ORD record
- ord-af063b938b3d4925925518104a1200e8
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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