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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 938483Generated: October 27, 2026

Trifluoroacetic acid → rac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid [4-(2-hydroxy-ethoxy)-phenyl]-amide

https://huagongshe.com/reaction/938483

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantDiphenylphosphinic chlorideHCID 73910—
Reactant2-(4-Aminophenoxy)ethanolHCID 80892—
ReactantDiisopropylethylamineHCID 81531—
Reactantrac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acidHCID 66625245—
Productrac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid [4-(2-hydroxy-ethoxy)-phenyl]-amideHCID 75985743—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-823d75b8caf44e08947c47429581bd9b
Source noteValidation data from https://doi.org/10.1039/C8SC04228D