3-Chloro-6-(trifluoromethyl)pyridazine → [5-Methyl-2-(trifluoromethyl)phenyl]-[3-[[6-(trifluoromethyl)pyridazin-3-yl]amino]pyrrolidin-1-yl]methanone
Reaction equation
[Cl:20][c:21]1[n:22][n:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]1.[NH2:1][CH:2]1[CH2:3][N:4]([C:7](=[O:8])[c:9]2[c:10]([C:16]([F:17])([F:18])[F:19])[cH:11][cH:12][c:13]([CH3:15])[cH:14]2)[CH2:5][CH2:6]1>>[NH:1]([CH:2]1[CH2:3][N:4]([C:7](=[O:8])[c:9]2[c:10]([C:16]([F:17])([F:18])[F:19])[cH:11][cH:12][c:13]([CH3:15])[cH:14]2)[CH2:5][CH2:6]1)[c:21]1[n:22][n:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]1Participants
3
Sources & evidence
- ORD record
- ord-2daacbb31f99485eb1decc12d900da1f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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