2-Methyl-1-pyrrolidin-2-ylmethyl-pyrrolidine → [2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-[2-[(2-methylpyrrolidin-1-yl)methyl]pyrrolidin-1-yl]methanone

HRID 938629Notes

Reaction equation

HRID 938629 reaction equation
[CH3:1][CH:2]1[N:3]([CH2:7][CH:8]2[NH:9][CH2:10][CH2:11][CH2:12]2)[CH2:4][CH2:5][CH2:6]1.[F:13][c:14]1[c:15]([C:16](=[O:17])[OH:18])[cH:19][cH:20][c:21]([B:23]2[O:24][C:25]([CH3:30])([CH3:31])[C:26]([CH3:28])([CH3:29])[O:27]2)[cH:22]1>>[CH3:1][CH:2]1[N:3]([CH2:7][CH:8]2[N:9]([C:16]([c:15]3[c:14]([F:13])[cH:22][c:21]([B:23]4[O:24][C:25]([CH3:30])([CH3:31])[C:26]([CH3:28])([CH3:29])[O:27]4)[cH:20][cH:19]3)=[O:17])[CH2:10][CH2:11][CH2:12]2)[CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 205810162-Methyl-1-pyrrolidin-2-ylmethyl-pyrrolidineHCID 447176654-Carboxy-3-fluorobenzeneboronic acid pinacol ester

Product 1

HCID 76694943[2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-[2-[(2-methylpyrrolidin-1-yl)methyl]pyrrolidin-1-yl]methanone

Sources & evidence

ORD record
ord-c945436cfc2741d7875b06baf52e0d95
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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