4-Methylsulfonylbenzylamine → 2-chloro-N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-(4-(methylsulfonyl)benzyl)terephthalamide
Reaction equation
[CH3:27][S:28](=[O:29])(=[O:30])[c:31]1[cH:32][cH:33][c:34]([CH2:37][NH2:38])[cH:35][cH:36]1.[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][c:10]1[C:11]([NH:12][c:13]1[cH:14][c:15](-[c:20]2[n:21][cH:22][cH:23][cH:24][cH:25]2)[c:16]([Cl:19])[cH:17][cH:18]1)=[O:26]>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:38][CH2:37][c:34]2[cH:33][cH:32][c:31]([S:28]([CH3:27])(=[O:29])=[O:30])[cH:36][cH:35]2)[cH:8][cH:9][c:10]1[C:11]([NH:12][c:13]1[cH:14][c:15](-[c:20]2[n:21][cH:22][cH:23][cH:24][cH:25]2)[c:16]([Cl:19])[cH:17][cH:18]1)=[O:26]Participants
3
Sources & evidence
- ORD record
- ord-c04487dea6274bb49f3ed529edc733ca
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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