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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 938665Generated: October 31, 2026

Tetrahydrofuran → 1-(3-Chloro-1-oxopropyl)-1,2-dihydro-4-[3-(trifluoromethyl)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile

https://huagongshe.com/reaction/938665

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant3-Chloropropionyl chlorideHCID 69364—
ReactantProton spongeHCID 88675—
ReactantHCID 14677507HCID 14677507—
Product1-(3-Chloro-1-oxopropyl)-1,2-dihydro-4-[3-(trifluoromethyl)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrileHCID 15712557—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-7bea956496bc452b8638abe4b7e73977
Source noteValidation data from https://doi.org/10.1039/C8SC04228D