2-(6-Chloroimidazo[1,2-b]pyridazin-2-yl)propan-2-ol → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[2-(1-hydroxy-1-methylethyl)imidazo[1,2-b]pyridazin-6-yl]amino}thiophene-3-carboxamide
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]2[n:6]([n:7]1)[cH:8][c:9]([C:11]([CH3:12])([CH3:13])[OH:14])[n:10]2.[F:15][c:16]1[c:17](-[c:27]2[cH:28][c:29]([C:33](=[O:34])[NH2:35])[c:30]([NH2:32])[s:31]2)[c:18]([F:26])[cH:19][c:20]([C:22]([CH3:23])([CH3:24])[OH:25])[cH:21]1>>[c:2]1([NH:32][c:30]2[c:29]([C:33](=[O:34])[NH2:35])[cH:28][c:27](-[c:17]3[c:16]([F:15])[cH:21][c:20]([C:22]([CH3:23])([CH3:24])[OH:25])[cH:19][c:18]3[F:26])[s:31]2)[cH:3][cH:4][c:5]2[n:6]([n:7]1)[cH:8][c:9]([C:11]([CH3:12])([CH3:13])[OH:14])[n:10]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8d2c7a5875334e938c7dfc1603717d75
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…