Ethanol → Methyl 6-(4-methylphenyl)-2-methylquinoline-3-carboxylate

HRID 938949Notes

Reaction equation

HRID 938949 reaction equation
[B:17]([O-:18])([O-:26])[O:27][c:19]1[cH:20][cH:21][c:22]([CH3:25])[cH:23][cH:24]1.[Br:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([C:13](=[O:14])[O:15][CH3:16])[c:7]([CH3:12])[n:8][c:9]2[cH:10][cH:11]1.[C:28](=[O:29])([O-:30])[O-:31].[CH2:35]([OH:36])[CH3:37].[K+:32].[K+:33].[OH2:34].[c:38]1([CH3:39])[cH:40][cH:41][cH:42][cH:43][cH:44]1>>[c:2]1(-[c:19]2[cH:20][cH:21][c:22]([CH3:25])[cH:23][cH:24]2)[cH:3][c:4]2[cH:5][c:6]([C:13](=[O:14])[O:15][CH3:16])[c:7]([CH3:12])[n:8][c:9]2[cH:10][cH:11]1

Participants

8

Reactant 7

HCID 702EthanolHCID 813Potassium Cation2×HCID 962WaterHCID 1140TolueneHCID 19660Carbonate IonHCID 18472460Methyl 6-bromo-2-methylquinoline-3-carboxylateHCID 866453334-Methylphenyl borate

Product 1

HCID 18472437Methyl 6-(4-methylphenyl)-2-methylquinoline-3-carboxylate

Sources & evidence

ORD record
ord-57c7cd8195954732843b4ac132b554fd
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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