1-(4-Phenyloxan-4-yl)methanamine → 3-fluoro-4-(2-(4-methylpyridin-2-ylamino)thiazol-5-ylthio)-N-((4-phenyltetrahydro-2H-pyran-4-yl)methyl)picolinamide
Reaction equation
[F:1][c:2]1[c:3]([C:22](=[O:23])[OH:24])[n:4][cH:5][cH:6][c:7]1[S:8][c:9]1[cH:10][n:11][c:12]([NH:14][c:15]2[n:16][cH:17][cH:18][c:19]([CH3:21])[cH:20]2)[s:13]1.[c:25]1([C:31]2([CH2:37][NH2:38])[CH2:32][CH2:33][O:34][CH2:35][CH2:36]2)[cH:26][cH:27][cH:28][cH:29][cH:30]1>>[F:1][c:2]1[c:3]([C:22](=[O:24])[NH:38][CH2:37][C:31]2([c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[CH2:32][CH2:33][O:34][CH2:35][CH2:36]2)[n:4][cH:5][cH:6][c:7]1[S:8][c:9]1[cH:10][n:11][c:12]([NH:14][c:15]2[n:16][cH:17][cH:18][c:19]([CH3:21])[cH:20]2)[s:13]1Participants
3
Sources & evidence
- ORD record
- ord-66db605ddc3647caab1afcfc042b35fd
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…