Acetone → Methyl 6-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-2-pyridinecarboxylate

HRID 939000Notes

Reaction equation

HRID 939000 reaction equation
[Br:24][CH2:25][c:26]1[c:27]([F:32])[cH:28][cH:29][cH:30][cH:31]1.[CH3:33][C:34](=[O:35])[CH3:36].[K+:18].[K+:19].[O-:20][C:21]([O-:22])=[O:23].[OH:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][cH:11][c:12]([C:14](=[O:15])[O:16][CH3:17])[n:13]2)[cH:6][cH:7]1>>[O:1]([c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][cH:11][c:12]([C:14](=[O:15])[O:16][CH3:17])[n:13]2)[cH:6][cH:7]1)[CH2:25][c:26]1[c:27]([F:32])[cH:28][cH:29][cH:30][cH:31]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 67968alpha-Bromo-o-fluorotolueneHCID 136146660Methyl 6-(4-hydroxyphenyl)-2-pyridinecarboxylate

Product 1

HCID 59468948Methyl 6-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-2-pyridinecarboxylate

Sources & evidence

ORD record
ord-214d0582e35f46108e3d2d27ac4212ee
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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