4-(4-Bromo-benzyl)-thiomorpholine 1,1-dioxide → 2-({4-[(1,1-Dioxidothiomorpholin-4-yl)methyl]phenyl}amino)-5-[4-(methyl sulfonyl)phenyl]thiophene-3-carboxamide

HRID 939173Notes

Reaction equation

HRID 939173 reaction equation
[Br:20][c:21]1[cH:22][cH:23][c:24]([CH2:25][N:26]2[CH2:27][CH2:28][S:29](=[O:32])(=[O:33])[CH2:30][CH2:31]2)[cH:34][cH:35]1.[NH2:1][c:2]1[s:3][c:4](-[c:10]2[cH:11][cH:12][c:13]([S:16](=[O:17])(=[O:18])[CH3:19])[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[cH:11][cH:12][c:13]([S:16](=[O:17])(=[O:18])[CH3:19])[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:21]1[cH:22][cH:23][c:24]([CH2:25][N:26]2[CH2:27][CH2:28][S:29](=[O:32])(=[O:33])[CH2:30][CH2:31]2)[cH:34][cH:35]1

Participants

3

Reactant 2

HCID 523254684-(4-Bromo-benzyl)-thiomorpholine 1,1-dioxideHCID 582564812-Amino-5-[4-(methylsulfonyl)phenyl]thiophene-3-carboxamide

Product 1

HCID 446083102-({4-[(1,1-Dioxidothiomorpholin-4-yl)methyl]phenyl}amino)-5-[4-(methyl sulfonyl)phenyl]thiophene-3-carboxamide

Sources & evidence

ORD record
ord-c51dd8c5beca4065aa861d3cb202e10c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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