3-(2-Methylphenyl)prop-2-enoic acid → N-[1-(5,5-difluorohexyl)pyrazol-3-yl]-3-(2-methylphenyl)prop-2-enamide
Reaction equation
[F:1][C:2]([CH2:3][CH2:4][CH2:5][CH2:6][n:7]1[n:8][c:9]([NH2:12])[cH:10][cH:11]1)([CH3:13])[F:14].[c:15]1([CH3:26])[c:16]([CH:21]=[CH:22][C:23](=[O:24])[OH:25])[cH:17][cH:18][cH:19][cH:20]1>>[F:1][C:2]([CH2:3][CH2:4][CH2:5][CH2:6][n:7]1[n:8][c:9]([NH:12][C:23]([CH:22]=[CH:21][c:16]2[c:15]([CH3:26])[cH:20][cH:19][cH:18][cH:17]2)=[O:24])[cH:10][cH:11]1)([CH3:13])[F:14]Participants
3
Sources & evidence
- ORD record
- ord-98b456de3fb8466ebffd9d8f18f2cd55
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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