Propargyl bromide → N-propargyloxy-tert-butyl-(dimethyl-tert-butylaminocarbonyl-methyl)-amine
Reaction equation
[C:20]([N:21]([C:22]([CH3:23])([CH3:24])[C:25]([NH:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[OH:32])([CH3:33])([CH3:34])[CH3:35].[CH2:1]([CH:2]=[CH2:3])[O:4][N:5]([C:6]([C:7](=[O:8])[NH:9][C:10]([CH3:11])([CH3:12])[CH3:13])([CH3:14])[CH3:15])[C:16]([CH3:17])([CH3:18])[CH3:19].[CH2:36]([Br:37])[C:38]#[CH:39]>>[CH2:1]([C:2]#[CH:3])[O:4][N:5]([C:6]([C:7](=[O:8])[NH:9][C:10]([CH3:11])([CH3:12])[CH3:13])([CH3:14])[CH3:15])[C:16]([CH3:17])([CH3:18])[CH3:19]Participants
4
Sources & evidence
- ORD record
- ord-11408128c11a4d2fa5d124322ff3d80b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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