Ethylene Glycol → 5-Bromospiro[indoline-3,4'-piperidin]-2-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[NH:7][C:6](=[O:11])[C:5]21[CH2:12][CH2:13][N:14]([C:17]#[N:18])[CH2:15][CH2:16]1.[CH2:25]([Cl:26])[Cl:27].[Na+:20].[OH-:19].[OH:21][CH2:22][CH2:23][OH:24]>>[Br:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[NH:7][C:6](=[O:11])[C:5]21[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1Participants
6
Sources & evidence
- ORD record
- ord-597f58ac4c944d44b889c68cf911d6b4
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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