1-Bromo-3-chlorobenzene → 2-(3-Chlorophenyl)-4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[F:9][c:10]1[cH:11][cH:12][c:13]([O:14][c:15]2[c:16](=[O:31])[nH:17][n:18][cH:19][c:20]2-[c:21]2[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:25][cH:26]2)[cH:32][cH:33]1>>[c:2]1(-[n:17]2[c:16](=[O:31])[c:15]([O:14][c:13]3[cH:12][cH:11][c:10]([F:9])[cH:33][cH:32]3)[c:20](-[c:21]3[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:25][cH:26]3)[cH:19][n:18]2)[cH:3][c:4]([Cl:8])[cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-0f3020076f204fd9abb2df36eb494754
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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